Diagnostic Role of Magnetic Resonance Cholangiopancreatography in Evaluation of Obstructive Jaundice

Abstract

The diagnostic utility of Magnetic Resonance Cholangiopancreatography (MRCP) has expanded substantially, establishing it as a preeminent, noninvasive primary imaging modality for the evaluation of obstructive jaundice. This investigation sought to determine the diagnostic utility of Magnetic Resonance Cholangiopancreatography (MRCP) in patients presenting with obstructive jaundice. Central to this inquiry was the precise measurement of the modality’s sensitivity and specificity for differentiating between neoplastic conditions and benign biliary obstructions. The study population consisted of 50 subjects with a mean age of 58.7 years (range: 23–90 years). Demographic profiling indicated that individuals aged 60 and above constituted approximately 50% of the cohort, with female patients constituted the majority. In terms of diagnostic yield, MRCP exhibited a high degree of fidelity when identifying choledocholithiasis; the technique yielded a diagnostic accuracy of 97.73%, accompanied by a sensitivity of 97.37% and a perfect specificity of 100%. The associated positive and negative predictive values (PPV and NPV) were calculated at 100% and 85.71%, respectively. Furthermore, the capacity of MRCP to identify malignant etiologies was absolute; the modality reached a 100% threshold for sensitivity, specificity, accuracy, and both predictive metrics