Physiological Effects of Age and Body Mass Index on Some Liver Function Tests in Postmenopausal Women

Ahmed H. AL-Hamdani — Wed, 01 Jul 2026 00:00:00 +0200

Menopause is an ordinary physiologic period in aged females. It is a usual situation that occurs at the long-lasting termination of the menstrual period because of the termination of the synthesis of fertility hormones from the ovary. Menopause is an order of aging usually associated with many events in her life, and as a part of aging, many processes stop permanently or change to accommodate this situation in life. The current study was analyzed the liver function tests represented as (Lactate dehydrogenase LDH, Aspartate aminotransferase AST, Alanine aminotransferase ALT, Alkaline phosphatase ALP, and estimated the De Ritis Ratio) in sera of 74 apparently well healthy volunteers females, including 33 apparently healthy premenopausal women age around (19-41) years old as a group of control and 41 apparently healthy postmenopausal female (the menopause occur ordinarily), aged old around (55-74) years old which divided into subcategories classified according to the age and body mass index (BMI) in order to identify the effect of age progressing and BMI on liver function tests according the elderly women. Regarding the results found in this work, there is the highest elevation in serum LDH, ALT, AST, and ALP enzyme in postmenopausal women when compared with a group of controls, and an important influence of BMI and age advances on these enzyme activities in postmenopausal women but no significant variations were found in the mean activity of ALT with increasing age in postmenopausal women. Lastly, the present results of the De Ritis Ratio recognized that there was no significant change in each contrast measured in this study. Liver enzyme elevation over a period is an important indicator of metabolic variations associated with the end of ovarian function and physical changes related to age and Body Mass Index. Furthermore, BMI appeared as a worthy predictor of elevated liver enzymes. The importance of this study is to express that changes happen in post-menopausal women related to normal physiological changes with progress age, not related to pathological conditions.

Incidence and Mortality Rates of Hodgkin's Lymphoma in the Western Region of Libya

Jbireal J M, Sana A. Alteer — Thu, 02 Jul 2026 00:00:00 +0200

Hodgkin lymphoma (HL) is a malignant disorder of the lymphatic system and represents an important subgroup of lymphoid neoplasms, which also include non-Hodgkin lymphoma (NHL), plasma cell neoplasms, and lymphoid leukemias. Differences in cancer incidence, mortality, diagnosis, and treatment outcomes between developed and developing countries highlight the need for local epidemiological studies. Due to the limited availability of documented research on lymphomas in Libya, this study aimed to investigate the incidence, clinical characteristics, and outcomes of HL patients while also presenting a rare familial case involving affected siblings. This retrospective documentary study was conducted using records from the oncology centers of Sabratha and Misurata between September 2023 and January 2024. A total of 872 lymphoma patients were reviewed, of whom 357 were diagnosed with HL. Male patients constituted a slightly higher proportion of HL cases than females, with mean ages of 36.83 and 34.91 years, respectively. Most HL cases originated from Misurata, followed by Tripoli and Khums. The highest disease frequency was observed among individuals aged 9–40 years, while fewer cases were recorded among older age groups. The overall mortality rate among lymphoma patients was low, with 19 deaths recorded among the 872 cases. Among HL patients, mortality was slightly higher in females than in males. The findings are consistent with international reports indicating a higher incidence of HL in males and a predominance of disease occurrence in younger adults. The study confirms important epidemiological and clinical characteristics of HL and NHL in Libya and emphasizes the need for further research to better understand the causes, risk factors, and prognosis of Hodgkin lymphoma, particularly in relation to its increasing epidemiological trends

Libyan Medical Journal

Physiological Effects of Age and Body Mass Index on Some Liver Function Tests in Postmenopausal Women

Incidence and Mortality Rates of Hodgkin's Lymphoma in the Western Region of Libya