Serum Calcium to Magnesium Ratio in Preeclamptic Women: A Cross-Sectional Study

Zina Abdullah Hussein, Amenah Fadhil, Ban Hussein Ibrahim, Wassan Nori — Fri, 24 Feb 2023 00:00:00 +0000

Preeclampsia is a syndrome that adversely affects maternal and fetal outcomes. Despite extensive re-search, PE's exact pathogenesis is still uncertain. Micronutrients like calcium (Ca) and Magnesium (Mg) hemostasis were linked to many adverse health issues, including PE Herein, we aimed to verify the role of Calcium, Magnesium, and Calcium to Magnesium Ratio among PE cases vs. healthy controls for a possible application in preventive approach. The study enrolled 81 pregnant women whose age and body index matched and divided into two groups; PE cases and healthy controls. Their demographic, urine, and serum Calcium, Magnesium was compared. Analysis showed serum Ca2+ level, mean serum Ca2+-Mg2+ratio in the patients was considerably lower than in controls; P=0.01 and P=0.04, re-spectively. Reduced Mg levels were recorded only in PE cases. Correlation confirmed a positive cor-relation with maternal age and is inversely linked with gestational age, Ca 2+, Mg2+, and Ca2+-Mg2+ ratio. The diastolic blood pressure was negatively correlated to the Ca2+-Mg2+ ratio. Defining mi-cronutrients during pregnancy and how this may affect maternal health is a promising avenue for PE prevention. Micronutrient profiling might help characterize preeclampsia prevention options.

The Role of Thiamine in the Management of Refractory Hy-poxemia, Refractory Hypotension and Shock in Critically Ill Covid-19 Patients

Usama Bensaad, Ahmed Atia — Mon, 13 Mar 2023 00:00:00 +0000

Dear editor, we would like to share you our experience regarding the management of re-fractory hypoxemia, refractory hypotension and shock in critically ill Covid-19 patients. We believe that, one of the main causes of the deterioration of Covid-19 patients could be malnutrition with vitamins depletion from the body. Many of these patients presented with loss of appetite and taste accompanied with poor oral intake for several days or even weeks. This will deplete the body resources from Macro-& micro-nutrients especially thi-amine, which can be deficient in 3-14 days particularly if the patient is already malnour-ished, taking anti-thiamine products (as coffee, tea), receiving Total Parenteral Nutrition (TPN), on Continuous Renal Replacement Therapy (CRRT), or had a bariatric surgery. From the daily practice, we have noticed that refractory hypoxemia, refractory hypoten-sion, or septic shock is exaggerated by Thiamine deficiency.

Libyan Medical Journal

Serum Calcium to Magnesium Ratio in Preeclamptic Women: A Cross-Sectional Study

The Role of Thiamine in the Management of Refractory Hy-poxemia, Refractory Hypotension and Shock in Critically Ill Covid-19 Patients