Effect of Marjoram Extract Containing Monoterpene Hydrocarbons, Oxygenated Monoterpene, and Phenolic Compounds on Some Gram-Positive and Gram-Negative Bacteria
DOI:
https://doi.org/10.69667/lmj.2517120Keywords:
Marjoram, Natural Plant, Extraction, Bioactive Substances, Antimicrobial Activity.Abstract
In the present study, an attempt has been made to study the chemical composition and antimicrobial activity of water and methanol extracts of Origanum Majorana against four types of bacteria, two-gram negative (E. Coil, S. typhi) and two-gram positive (B.sub, s.aur) using agar well diffusion method. Flavonoids, tannins, anthraquinones, terpenes, coumarins, alkaloids, and saponins were the primary bioactive substances identified in Origanum majorana. The antibacterial activity revealed that the methanol extract of Origanum majorana only inhibited Bacillus subtilis and Staphylococcus aureus. However, some bacteria did not exhibit extract resistance. According to the current study, Origanum majorana extract may be a promising option for the hunt for a natural antibacterial agent. The scientific knowledge gained from this investigation will help determine the antibacterial values and explore additional pharmacological features.
في الدراسة الحالية تم دراسة التركيب الكيميائي والنشاط المضاد للميكروبات لمستخلصات الماء والميثانول من المردقوش ضد أربعة أنواع من البكتيريا، اثنان سلبيان للجرام واثنان موجبان للجرام باستخدام طريقة انتشار الآبار في الأجار. المواد النشطة البيولوجية الأولية الفعالة التي تم تحديددها من خلال الدراسة في نبات المردقوش هي الفلافونويدات والتانينات والأنثراكينونات والتربينات والكومارين والقلويدات كشف النشاط المضاد للبكتيريا أن مستخلص الميثانول من المردقوش يثبط Bacillus subtilis و Staphylococcus aureus. فقظ. ومع ذلك، لم تظهر بعض البكتيريا مقاومة للمستخلص. وفقًا للدراسة الحالية، قد يكون مستخلص المردقوش خيارًا واعدًا للبحث عن عامل طبيعي مضاد للبكتيريا. ستساعد المعرفة العلمية المكتسبة من هذا البحث في تحديد قيم مضادات البكتيريا واستكشاف ميزات دوائية إضافية.
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