Comparative Prospective Study on Prophylactic Antibiotics versus Empirical Antibiotics in the Prevention of Surgical Site Infection in Libya
DOI:
https://doi.org/10.69667/lmj.2517309Keywords:
Surgical Site Infections, Antimicrobial Prophylaxis, Empirical Antibiotics, Wound InfectionAbstract
Surgical site infections (SSIs) develop in or around a surgical wound after the operation depending on the type of procedure performed. One of the main strategies to prevent SSIs is the use of antimicrobial prophylaxis, which is the administration of antibiotics before, during, or after surgery to reduce the risk of wound infections. However, there is controversy about the optimal duration and regimen of antimicrobial prophylaxis. This study aims to investigate and compare the use of prophylactic antibiotics versus empirical antibiotics in preventing SSIs. A prospective observational study was conducted in secondary health center of Aljabal Alakhter in Libya from December 2020 to October 2022. A total of 96 cases were enrolled in the study. Out of whom,46 patients with a mean age of 40.59 (±13.848) years for Prophylactic group and 50 patients with a mean age 31.02 (±17.694) years for Empirical group. Prophylactic group had 17 males and 29 females, while Empirical group had 21 males and 29 females. There was statistically non-significant difference between gender distributions in the two groups. In conclusion: SSIs are one of the most common post operative complications in which a high risk of post operative morbidity and mortality, prolongs hospital stay and raises hospital cost to patients. In our study, the total incidence rate of SSI was 0.0%. While empirical use of antibiotics is of minimal benefit.
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