Nevus Lipomatosus Cutaneous Superficialis: A Case Report from Tripoli, Libya

Abstract

Nevus lipomatosus cutaneous superficialis (NLCS) is a rare benign hamartomatous lesion characterized by ectopic mature adipocytes within the dermis. We present the case of a 24‑year‑old Libyan male with asymptomatic, multiple, soft, yellowish papules and nodules localized to the left buttock. The lesions had been present for several years and gradually increased in size. Systemic examination and laboratory findings were unremarkable. Histopathological analysis revealed clusters of mature adipocytes interspersed among dermal collagen bundles and surrounding subpapillary vessels, extending into the papillary dermis. The clinical and histological features were consistent with classical NLCS. The condition is benign, with no systemic associations or malignant potential. Treatment is unnecessary unless for cosmetic reasons, with surgical excision or CO₂ laser ablation as options. To the best of our knowledge, this is the second case reported in Tripoli, contributing to the limited regional literature and reinforcing the importance of recognizing NLCS to avoid misdiagnosis and unnecessary interventions