Determine the Potential Risk of High Blood Pressure Causes Abortion in Pregnancies with Polycystic Ovary Syndrome in Aljouf, Saudi Arabia

Abstract

To determine the risk of abortion in pregnant women with and without concomitant PCOS. Between January 2021 and December 2021 in Sakaka, Aljouf, Saudi Arabia, we conducted a retrospective case control research on pregnant women with and without PCOS at the Obstetric department of Maternity and Children hospital (MCH). 174 pregnant women in total were separated into case (n = 149) and control (n = 25) based on the presence or absence of PCOS. Age, BMI, a history of PCOS, follow-up prenatal care, and natural conception were among the inclusion criteria. We evaluated initial diagnosis of PCOS in case group 18.1% in age 16-26, 65.7% in 27-36 and 16.1% in age 37-46. The mean BMI of case and control groups found 30.21 ± 1.2 and23.24 ± 2.2 respectively. The age different of first pregnancy found higher significant in between them at p value =0.001. while history of abortion 42.2% higher in cases than controls (p=0.001). The 75.1 %, 61%, 85.2% history of hypertension, Dyslipidemia and Diabetes mellitus in case which indicated higher significant compared to the control (p =0.000). Multiple logistic regression using analysis identified some characteristics substantially connected to PCOS pregnancy that were: H/of abortion (adj. OR= 3.69, 95%CI: 1.35 to 9.61, p<0.001), H/of hy-pertension (adj. OR=4.59, 95%CI: 1.42 to 9.65, 0.000), H/of diabetes mellitus (adj OR= 2.67, 95%CI: 1.11 to 6.59, p=0.056) and as well as H/of Dyslipidemia (adj. OR=3.46, 95%CI: 1.89 to 6.87, p=0.000). The findings of the hospital-based study have shown that pre-pregnancy PCOS is a major and independent risk factor for a pregnant woman's eventual abortion.