Case Presentation: Remission of an Acute Thrombotic Throm-bocytopenic Purpura in a Previously Healthy Female Adult

Authors

  • Ahmed Algeblawi Department of Internal Medicine, Tripoli Central Hospital, Tripoli, Libya.
  • Abdullatef Khmmaj Department of Internal Medicine, Tripoli Central Hospital, Tripoli, Libya.
  • Imhemed Mealif Department of Internal Medicine, Tripoli Central Hospital, Tripoli, Libya.
  • Mohamed Esaadi Department of Internal Medicine, Tripoli Central Hospital, Tripoli, Libya.

Abstract

We reported a female patient presenting with headache, right side body weakness with multiple bruises all over her body. Over reviewing of her laboratory investigations, the patient had evidence of micro-angiopathic haemolytic anaemia (MAHA) and thrombocytopenia. Thrombotic thrombocytopenic purpura (TTP) was suspected. Corticosteroids and rituximab were started urgently. The patient had a dramatic improvement to the treatment of rituximab. A disintegrin and metalloproteinase with throm-bospondin type 1 motifs, member 13 (ADAMTS 13) activity was remarkably low with a positive inhibitory ADAMTS 13 antibody. Subsequently, the patient routine investigations showed a complete remission of her pancytopenia with excellent improvement of her overall health to rituximab as a first line treatment.

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Published

2023-10-19

How to Cite

Ahmed Algeblawi, Abdullatef Khmmaj, Imhemed Mealif, & Mohamed Esaadi. (2023). Case Presentation: Remission of an Acute Thrombotic Throm-bocytopenic Purpura in a Previously Healthy Female Adult. Libyan Medical Journal, 31–37. Retrieved from https://lmj.ly/index.php/ojs/article/view/29

Issue

Volume 15, Issue 2, 2023

Section

Articles