Efficiency of Cynara Cornigera Fruits on Antibacterial, Antifungal and Its Phytochemical, Anti-Oxidant Screening
DOI:
https://doi.org/10.69667/lmj.2517119Keywords:
Cynara Cornigera, Antibacterial, Phytochemical, Antioxidant.Abstract
The Cynara Cornigera is one of the most plants growing naturally in many of Libyan areas. Its fruits were widely consumed due to interesting taste, so the local population used it in a variety of medical applications. In this the Cynara Cornigera fruits were selected to investigate the efficiency of some extracts (aqueous and alcohol) against Gram-positive bacteria of (Staphylococcus aureus, Bacillus cereus, and Streptococcus pneumonia) and Gram-negative (Escherichia coli and Proteus vulgaris), besides some fungal specie including Aspergilla's niger., also the phytochemical, total phenols and antioxidant activities were detected. The results recorded that the plant fruits containing many natural product constituents such as carbohydrates and/or glycosides, flavonoids, sterols and/or triterpenes, and cardiac glycoside, there are small variations of their contents in aqueous and alcoholic extracts. For the antibacterial activities, higher concentrations of extracts of (0.1 – 0.8 g/ 100 ml) showed high effects compared with lower ones of (0.0001 – 0.1 g/ 100 ml) against the selected bacteria in this study. The contents of total phenols were 648.61 and 178.5 mg/ml in Alcohol and aqueous extracts, respectively, while the anti- oxidant capacity was 45.20 mg/ml. The study concluded that the presence of natural product compounds mainly the main reason for the inhibition of bacteria and the different effects were attributed to the effect of solvent polarizes during the extraction.
يُعد نبات القنطريون من أكثر النباتات نموًا طبيعيًا في العديد من المناطق الليبية. وقد استُهلكت ثماره على نطاق واسع نظرًا لمذاقه اللذيذ، مما دفع السكان المحليين إلى استخدامه في تطبيقات طبية متنوعة. وفي هذا الصدد، تم اختيار ثمار القنطريون لدراسة فعالية بعض المستخلصات (المائية والكحولية) ضد البكتيريا موجبة الجرام (المكورات العنقودية الذهبية، والعصوية الشمعية، والعقدية الرئوية)، وسالبة الجرام (الإشريكية القولونية والبروتيوس الشائع)، بالإضافة إلى بعض أنواع الفطريات، بما في ذلك الرشاشيات السوداء. كما تم الكشف عن النشاط الكيميائي النباتي، والفينولات الكلية، ومضادات الأكسدة. سجلت النتائج أن ثمار النبات تحتوي على العديد من مكونات المنتج الطبيعي مثل الكربوهيدرات و/أو الجليكوسيدات والفلافونويدات والستيرولات و/أو التربينات والجليكوسيدات القلبية، وهناك اختلافات طفيفة في محتوياتها في المستخلصات المائية والكحولية. بالنسبة للأنشطة المضادة للبكتيريا، أظهرت التركيزات الأعلى من المستخلصات (0.1 - 0.8 جم / 100 مل) تأثيرات عالية مقارنة بالتركيزات المنخفضة (0.0001 - 0.1 جم / 100 مل) ضد البكتيريا المختارة في هذه الدراسة. كان محتوى الفينولات الكلية 648.61 و 178.5 ملجم / مل في الكحول والمستخلصات المائية على التوالي، بينما كانت السعة المضادة للأكسدة 45.20 ملجم / مل. وخلصت الدراسة إلى أن وجود مركبات المنتج الطبيعي هو السبب الرئيسي في تثبيط البكتيريا وأن التأثيرات المختلفة تُعزى إلى تأثير استقطاب المذيبات أثناء الاستخلاص
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